We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Nebulized medications in the emergency department: A narrative review of nontraditional agents.
- Authors
Weant, Kyle A; Baum, Regan A; Hile, Garrett B; Humphries, Roger L; Metts, Elise L; Miller, Amy R; Woolum, Jordan A; Bailey, Abby M
- Abstract
Purpose This article summarizes emerging nontraditional therapies administered via the nebulization route for use in the emergency department (ED). Summary Although traditional routes of medication administration (eg, intravenous) have been the mainstay of administration modalities for decades, these routes may not be appropriate for all patients. Nowhere is this more readily apparent than in the ED setting, where patients with a variety of presentations receive care. One unique route for medication administration that has increasingly gained popularity in the ED is that of aerosolized drug delivery. This route holds promise as direct delivery of medications to the site of action could yield a more rapid and effective therapeutic response while also minimizing systemic adverse effects by utilizing a fraction of the systemic dose. Medication administration via nebulization also provides an alternative that is conducive to rapid, less invasive access, which is advantageous in the emergent setting of the ED. This review is intended to analyze the existing literature regarding this route of administration, including the nuances that can impact drug efficacy, as well as the available literature regarding novel, noncommercial nebulized medication therapy given in the ED. Conclusion Multiple medications have been investigated for administration via this route, and when implementing any of these therapies several practical considerations must be taken into account, from medication preparation to administration, to ensure optimal efficacy while minimizing adverse effects. The pharmacist is an essential bedside team member in these scenarios to assist with navigating unique and complex nuances of this therapy as they develop.
- Subjects
PREVENTION of drug side effects; DRUG administration routes; DRUG efficacy; FUROSEMIDE; NARCOTICS; SODIUM bicarbonate; HOSPITAL emergency services; AEROSOLS; NITROGLYCERIN; PHARMACOLOGY; NEBULIZERS &; vaporizers; NALOXONE; MAGNESIUM; KETAMINE; INHALATION administration; ALTERNATIVE medicine; PATIENT safety
- Publication
American Journal of Health-System Pharmacy, 2024, Vol 81, Issue 4, p88
- ISSN
1079-2082
- Publication type
Article
- DOI
10.1093/ajhp/zxad273