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- Title
Hs-CRP as an independent marker for cardiovascular diseases: A Correlation analysis.
- Authors
Jain, Vivek Kumar; Sharma, Dharmveer; Pandit, Vidyanand
- Abstract
Introduction: The advent of high-sensitivity C-reactive protein (Hs-CRP) assays has enhanced the utility of this acute-phase reactant in forecasting initial cardiovascular events. Elevated HsCRP levels are partially indicative of the extent of myocardial injury and can serve as predictors of both short-term and long-term outcomes in patients experiencing acute myocardial infarction. The study aims to investigate the relationship between elevated Hs-CRP levels and various traditional risk factors, including age, sex, lifestyle, and comorbidities. Materials and Methods: A prospective cross-sectional study involving 123 patients with traditional risk factors and pre-existing cardiovascular conditions was conducted at a tertiary care center. Hs-CRP levels were measured using immunoturbidimetric methods, and statistical correlations were performed. The statistical analysis was carried out using SPSS version 21 software. Results: Out of 123 patients, 82 had Hs-CRP levels exceeding 3 mg/L, while 41 patients had HsCRP levels below 3 mg/L. A total of 36.59% of the patients were in the age group of 51–60 years, with the majority (78.05%) being male. Among the individual lifestyle factors and traditional risk factors evaluated, five parameters—sedentary lifestyle, smoking, pre-existing hypertension, diabetes mellitus, and electrocardiographic changes—were found to be statistically significant. The correlation between elevated Hs-CRP levels and cardiovascular disease was also statistically significant. Conclusion: Hs-CRP is an independent biomarker for cardiovascular disease, with a significant positive correlation established between elevated Hs-CRP levels and major traditional risk factors such as sedentary lifestyle, smoking, hypertension, and diabetes mellitus.
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2024, Vol 15, Issue 8, p743
- ISSN
0975-3583
- Publication type
Article