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- Title
A single aldehyde group can serve as a structural element for recognition by transmembrane protein CD36.
- Authors
Tsuzuki, Satoshi; Amitsuka, Takahiko; Okahashi, Tatsuya; Kozai, Yuki; Matsumura, Shigenobu; Inoue, Kazuo; Fushiki, Tohru
- Abstract
Transmembrane protein CD36 is considered to bind its distinct ligands such as long-chain fatty acids primarily by recognizing their terminal carboxyl moiety. In this study, we provide evidence that long-chain fatty aldehydes, such as oleic aldehyde, can be recognized by CD36. We suggest that a single aldehyde group may also serve as one of the structural elements recognizable by CD36.
- Subjects
ALDEHYDES; FUNCTIONAL groups; MEMBRANE proteins
- Publication
Bioscience, Biotechnology & Biochemistry, 2016, Vol 80, Issue 7, p1375
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1080/09168451.2016.1151343