We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Enantioselective C−H Olefination of α-Hydroxy and α-Amino Phenylacetic Acids by Kinetic Resolution.
- Authors
Xiao, Kai ‐ Jiong; Chu, Ling; Yu, Jin ‐ Quan
- Abstract
Significant progress has been made in the past decade regarding the development of enantioselective C−H activation reactions by desymmetrization. However, the requirement for the presence of two chemically identical prochiral C−H bonds represents an inherent limitation in scope. Reported is the first example of kinetic resolution by a palladium(II)-catalyzed enantioselective C−H activation and C−C bond formation, thus significantly expanding the scope of enantioselective C−H activation reactions.
- Subjects
ENANTIOSELECTIVE catalysis; OLEFINATION reactions; ORGANIC synthesis; KINETIC resolution; PALLADIUM catalysts
- Publication
Angewandte Chemie, 2016, Vol 128, Issue 8, p2906
- ISSN
0044-8249
- Publication type
Article
- DOI
10.1002/ange.201510808