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- Title
Novel pharmacological agents targeting memory and cognition in the treatment of anxiety disorders.
- Authors
Nandhra, Harpal Singh; Murphy, Catherine Louise; Sule, Akeem
- Abstract
Objective The aim of this study is to review data for several promising novel pharmacological drugs for anxiety disorders and describe how they exert their effects. Method We presented a review of the published literature. Online search plus reference list checking was also used. Results The neurobiology of anxiety is overviewed. N-methyl-D-aspartate and beta adrenaline are involved in memory consolidation. We describe studies using memantine, D-cycloserine, propranolol, and riluzole that modulate these pathways. Conclusion There are a number of promising new therapies, but these require further studies before they can enter routine clinical practice. Copyright © 2013 John Wiley & Sons, Ltd.
- Subjects
ANXIETY disorders treatment; COGNITION disorders treatment; METHYL aspartate; NEUROBIOLOGY; DRUG therapy; THERAPEUTICS
- Publication
Human Psychopharmacology: Clinical & Experimental, 2013, Vol 28, Issue 6, p538
- ISSN
0885-6222
- Publication type
Article
- DOI
10.1002/hup.2348