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- Title
Malignant versus benign mediastinal lesions: quantitative assessment with diffusion weighted MR imaging.
- Authors
Gümüstas S; Inan N; Sarisoy HT; Anik Y; Arslan A; Ciftçi E; Akansel G; Demirci A; Gümüştaş, Sevtap; Inan, Nagihan; Sarisoy, Hasan Tahsin; Anik, Yonca; Arslan, Arzu; Ciftçi, Ercüment; Akansel, Gür; Demirci, Ali
- Abstract
<bold>Objectives: </bold>We aimed to evaluate the performance of diffusion-weighted magnetic resonance imaging in differentiating malignant from benign mediastinal lesions.<bold>Methods: </bold>Fifty-three mediastinal lesions were examined with T1- and T2-weighted (W) conventional images. Then, two diffusion-weighted images were obtained with b = 0 and 1000 s/mm² values and apparent diffusion coefficients (ADC) were calculated. The statistical significance of differences between measurements was tested using the Student-t test.<bold>Results: </bold>The mean ADC of malignant lesions was significantly lower than that of the benign masses (p < 0.001). The cut-off value of ≤ 1.39 × 10(-3) mm²/s indicated a malignant lesion with a sensitivity of 95% and specificity of 87%.<bold>Conclusion: </bold>Diffusion-weighted imaging may be helpful in differentiating benign from malignant mediastinal masses.
- Publication
European Radiology, 2011, Vol 21, Issue 11, p2255
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-011-2180-9