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- Title
Changes in AVM angio-architecture and hemodynamics after stereotactic radiosurgery assessed by dynamic MRA and phase contrast flow assessments: a prospective follow-up study.
- Authors
Schuster L; Schenk E; Giesel F; Hauser T; Gerigk L; Zabel-Du-Bois A; Essig M; Schuster, Lydia; Schenk, E; Giesel, F; Hauser, T; Gerigk, L; Zabel-Du-Bois, A; Essig, Marco
- Abstract
<bold>Objectives: </bold>Assessment of changes in the hemodynamics of Arteriovenous malformations (AVM) induced by radiosurgery by MR Phase contrast (PC) measurements of the internal carotid arteries (ICA).<bold>Methods: </bold>65 patients shortly after or before stereotactic radiosurgery underwent MRI including morphological series, MR-Angiography (Time-of-flight, dynamic MRA) and bilateral ECG triggered MR phase contrast (PC) measurements of the ICA. Follow-up was performed in 34 patients. The observation period was up to 4 years.<bold>Results: </bold>Over all subjects, a significant relationship between mean arterial blood flow in the ICA on the side of the lesion and AVM volume was revealed (p = 0,0002). In large (>10 ccm) and medium-sized AVMs, (>3, 5 ≤ 10 ccm) the blood flow was significantly increased on the side of the AVM (p = 0,0004; p = 0,047), whereas in lesions <3, 5 ccm, no significant rise of the mean blood flow was detectable. At follow-up, the mean blood flow in the ipsilateral artery was not increased anymore compared to the contralateral ICA (p = 0,11). These changes correlated with a significant reduction of the average AVM volume (p = 0, 0026).<bold>Conclusions: </bold>The AVM angioarchitecture has significant impact on the blood flow in feeding arteries. A significant reduction of the shunt volume by successful radiotherapy leads to normalization of the hemodynamics.
- Publication
European Radiology, 2011, Vol 21, Issue 6, p1267
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-010-2031-0