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- Title
Computed tomography adnexal mass score to estimate risk for ovarian cancer.
- Authors
Santoso, Joseph; Robinson, Aimee; Suganda, Sri; Praservit, Sirinya; Wan, Jim; Ueland, Fred
- Abstract
Objective: We wish to develop a CT scan-based scoring system which estimates the probability of adnexal mass malignancy. Methods: Patients (324) undergoing adnexal mass surgery were recruited into the study from June 1, 2002, to January 1, 2009. All study patients had a preoperative CT scan and serum CA-125 test. CT scan abnormalities included any solid tumor components, ascites, and pelvic or abdominal lymphadenopathy and omental caking. Results: There were 225 (70 %) benign and 99 (30 %) malignant ovarian masses. Using logistic regression with the area under the curve of the receiver operating curve of 82 %, the cancer probability was determined by the equation.where A = age, B = CA-125, C = solid adnexal mass is 1 and cystic is 0, D = ascites is 1, E = omental caking is 1 and absence is 0, F = node size ≥1 cm is 1 and <1 cm is 0 value. The natural logarithm e is a constant [2.718281828]. For example, for a woman of age 60, CA-125 = 50 U/mL, with solid adnexal mass, ascites, omental caking, and lymphadenopathy, the probability is 0.994. Hence, this woman has a 99.4 % probability of having cancer. Conclusion: The computed tomography adnexal mass score combines CT scan findings, CA-125, and patient age into an equation to predict the malignant probability of an adnexal mass.
- Subjects
COMPUTED tomography; OVARIAN cancer; PROBABILITY theory; PREOPERATIVE care; HIV; LOGISTIC regression analysis; ADNEXAL diseases
- Publication
Archives of Gynecology & Obstetrics, 2014, Vol 289, Issue 3, p595
- ISSN
0932-0067
- Publication type
Article
- DOI
10.1007/s00404-013-3013-7