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- Title
Complete genome analysis of a highly pathogenic H5N1 influenza A virus isolated from a tiger in China.
- Authors
Mushtaq, Muhammad; Juan, Huang; Jiang, Ping; Li, Yufeng; Li, TianXian; Du, Yijun; Mukhtar, Muhammad
- Abstract
An influenza A virus (A/Tig/SH/01/2005 (H5N1) was isolated from lung tissue samples of a dead zoo tiger with respiratory disease in China in July 2005. Complete genome analysis indicated that the isolate was highly identical to an H5N1 virus isolated from a migratory duck at Poyang lake in China in that year. The genotype of the isolate was K,G,D,5J,F,1J,F,1E, and phylogenetically it was a clade 2.2 virus. Molecular characterization of all of the gene segments revealed characteristics of highly pathogenic influenza A viruses. These results may help to identify molecular determinants of virulence and highlight the necessity for continuous surveillance.
- Subjects
CHINA; INFLUENZA A virus; TIGERS; DUCKS; GENETIC polymorphisms; PHYLOGENY
- Publication
Archives of Virology, 2008, Vol 153, Issue 8, p1569
- ISSN
0304-8608
- Publication type
Report
- DOI
10.1007/s00705-008-0145-3