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- Title
Effects of dialyser and dialysate on the acute phase reaction in clinical bicarbonate dialysis.
- Authors
Schouten, Wilhelmina E. M.; Grooteman, Muriel P. C.; van Houte, Arend-Jan; Schoorl, Margreet; van Limbeek, Jacques; Nubé, Menso J.
- Abstract
Background. In chronic haemodialysis (HD), morbidity may result from repetitive induction of the acute phase response, caused by a bioincompatible dialysis membrane and/or contaminated dialysate. In the present study, cytokine release (interleukin-6, IL-6) and subsequent production of acute phase proteins (C-reactive protein, CRP and secretory phospholipase A2, sPLA2) were assessed to investigate whether the HD-induced acute phase reaction depends mainly on the type of membrane or on the sterility of the dialysate.
- Publication
Nephrology Dialysis Transplantation, 2000, Vol 15, Issue 3, p379
- ISSN
0931-0509
- Publication type
Article
- DOI
10.1093/ndt/15.3.379