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The level of DLDB/CHIP controls the activity of the LIM homeodomain protein Apterous: evidence for a functional tetramer complex in vivo.
- Published in:
- EMBO Journal, 2000, v. 19, n. 11, p. 2602, doi. 10.1093/emboj/19.11.2602
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- Publication type:
- Article
The relative expression amounts of apterous and its co-factor dLdb/Chip are critical for dorso-ventral compartmentalization in the Drosophila wing.
- Published in:
- EMBO Journal, 1998, v. 17, n. 23, p. 6846, doi. 10.1093/emboj/17.23.6846
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- Publication type:
- Article
The SMOC1‐matrisomal proteomics network M42 controls brain homeostasis and modulates toxicity in fly Alzheimer's Disease models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079106
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- Publication type:
- Article
The cytoskeletal protein Plectin regulates Tau‐induced neurotoxicity in Alzheimer's Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078952
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- Publication type:
- Article
Statistical Physics of Fitness Landscapes Finds Risk Genes Specific to Different AD Genetic Backgrounds.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076960
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- Publication type:
- Article
Functional Variants Identify Sex Specific Genes and Pathways in Alzheimer's Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076662
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- Publication type:
- Article
The SMOC1‐matrisomal proteomics network M42 controls brain homeostasis and modulates toxicity in fly Alzheimer's Disease models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079106
- By:
- Publication type:
- Article
The cytoskeletal protein Plectin regulates Tau‐induced neurotoxicity in Alzheimer's Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078952
- By:
- Publication type:
- Article
Statistical Physics of Fitness Landscapes Finds Risk Genes Specific to Different AD Genetic Backgrounds.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076960
- By:
- Publication type:
- Article
Functional Variants Identify Sex Specific Genes and Pathways in Alzheimer's Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076662
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- Publication type:
- Article
A matrisomal proteomics network modulates tau and amyloid‐beta toxicity in fly AD models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.065708
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- Publication type:
- Article
Systems genetic dissection of Alzheimer's disease brain gene expression networks.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.058716
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- Publication type:
- Article
Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 5, p. 831, doi. 10.1002/alz.12240
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- Publication type:
- Article
Identifying genetic modifiers of APOE in Alzheimer's disease using evolutionary information and regression analyses: Genetics/genetic factors of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043497
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- Publication type:
- Article
P4‐493: IDENTIFYING GENETIC MODIFIERS OF APOE VIA IMPUTATION OF DEVIATION IN EVOLUTIONARY ACTION LOAD IN ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1502, doi. 10.1016/j.jalz.2019.08.039
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- Publication type:
- Article
Downregulation of glial genes involved in synaptic function mitigates Huntington’s disease pathogenesis.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.64564
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- Publication type:
- Article
Inhibition of PIP4Kg ameliorates the pathological effects of mutant huntingtin protein.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.29123.001
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- Publication type:
- Article
TRIM28 regulates the nuclear accumulation and toxicity of both alpha- synuclein and tau.
- Published in:
- eLife, 2016, p. 1, doi. 10.7554/eLife.19809
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- Publication type:
- Article
A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity.
- Published in:
- eLife, 2015, p. 1, doi. 10.7554/eLife.05449
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- Publication type:
- Article
Influence of preoxidizing treatments on the preparation of iron-containing activated carbons for catalytic wet peroxide oxidation of phenol.
- Published in:
- Journal of Chemical Technology & Biotechnology, 2012, v. 87, n. 7, p. 880, doi. 10.1002/jctb.2744
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- Publication type:
- Article
Dual targeting of brain region‐specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1.
- Published in:
- EMBO Journal, 2021, v. 40, n. 7, p. 1, doi. 10.15252/embj.2020106106
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- Publication type:
- Article
Tau loss reduces hyperexcitability in mouse and drosophila genetics models of epilepsy
- Published in:
- 2012
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- Publication type:
- Abstract
Drosophila researchers focus on human disease.
- Published in:
- 2007
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- Publication type:
- Proceeding
SPA-STOCSY: an automated tool for identifying annotated and non-annotated metabolites in high-throughput NMR spectra.
- Published in:
- Bioinformatics, 2023, v. 39, n. 10, p. 1, doi. 10.1093/bioinformatics/btad593
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- Publication type:
- Article
Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease.
- Published in:
- Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0333-4
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- Publication type:
- Article
Functional variants identify sex-specific genes and pathways in Alzheimer's Disease.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38374-z
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- Publication type:
- Article
TORC1 Inhibition by Rapamycin Promotes Antioxidant Defences in a Drosophila Model of Friedreich’s Ataxia.
- Published in:
- PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0132376
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- Publication type:
- Article
Novel and Versatile Cobalt Azobenzene‐Based Metal‐Organic Framework as Hydrogen Adsorbent.
- Published in:
- ChemPhysChem, 2019, v. 20, n. 10, p. 1334, doi. 10.1002/cphc.201801151
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- Publication type:
- Article
The Drosophila FMRP and LARK RNA-Binding Proteins Function Together to Regulate Eye Development and Circadian Behavior.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 41, p. 10200, doi. 10.1523/JNEUROSCI.2786-08.2008
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- Publication type:
- Article
Huntingtin proteolysis releases non-polyQ fragments that cause toxicity through dynamin 1 dysregulation.
- Published in:
- EMBO Journal, 2015, v. 34, n. 17, p. 2255, doi. 10.15252/embj.201490808
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- Publication type:
- Article
Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases.
- Published in:
- Nature Cell Biology, 2007, v. 9, n. 4, p. 402, doi. 10.1038/ncb1553
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- Publication type:
- Article
Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity.
- Published in:
- PLoS Genetics, 2023, v. 19, n. 5, p. 1, doi. 10.1371/journal.pgen.1010760
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- Publication type:
- Article
Influence of chemical composition of the open bimetallic sites of MOF-74 on H adsorption.
- Published in:
- Adsorption, 2015, v. 21, n. 8, p. 589, doi. 10.1007/s10450-015-9707-3
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- Publication type:
- Article
Effect of Ion-Exchange Modification on Hydrogen and Carbon Dioxide Adsorption Behaviour of RhoZMOF Material.
- Published in:
- Adsorption Science & Technology, 2012, v. 30, n. 8/9, p. 793, doi. 10.1260/0263-6174.30.8-9.793
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- Publication type:
- Article
An altered extracellular matrix–integrin interface contributes to Huntington's disease-associated CNS dysfunction in glial and vascular cells.
- Published in:
- Human Molecular Genetics, 2023, v. 32, n. 9, p. 1483, doi. 10.1093/hmg/ddac303
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- Publication type:
- Article
Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinson's disease genes.
- Published in:
- Human Molecular Genetics, 2023, v. 32, n. 4, p. 685, doi. 10.1093/hmg/ddac230
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- Publication type:
- Article
Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.
- Published in:
- Science Translational Medicine, 2014, v. 6, n. 268, p. 1, doi. 10.1126/scitranslmed.3010523
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- Publication type:
- Article
Identification of genes that modify ataxin-1-induced neurodegeneration.
- Published in:
- Nature, 2000, v. 408, n. 6808, p. 101, doi. 10.1038/35040584
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- Publication type:
- Article
Tau polarizes an aging transcriptional signature to excitatory neurons and glia.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.85251
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- Publication type:
- Article
Spinocerebellar Ataxia Type 1 protein Ataxin-1 is signaled to DNA damage by ataxia-telangiectasia mutated kinase.
- Published in:
- Human Molecular Genetics, 2021, v. 30, n. 8, p. 706, doi. 10.1093/hmg/ddab074
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- Publication type:
- Article
Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease.
- Published in:
- Human Molecular Genetics, 2019, v. 28, n. 12, p. 2014, doi. 10.1093/hmg/ddz034
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- Publication type:
- Article
PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1.
- Published in:
- Human Molecular Genetics, 2018, v. 27, n. 16, p. 2863, doi. 10.1093/hmg/ddy200
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- Publication type:
- Article
Metal Homeostasis Regulators Suppress FRDA Phenotypes in a Drosophila Model of the Disease.
- Published in:
- PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0159209
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- Publication type:
- Article
Identification of NUB1 as a suppressor of mutant Huntingtin toxicity via enhanced protein clearance.
- Published in:
- Nature Neuroscience, 2013, v. 16, n. 5, p. 562, doi. 10.1038/nn.3367
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- Publication type:
- Article
Smaug/SAMD4A Restores Translational Activity of CUGBP1 and Suppresses CUG-Induced Myopathy.
- Published in:
- PLoS Genetics, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.pgen.1003445
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- Publication type:
- Article
A Genome-Scale RNA--Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease.
- Published in:
- PLoS Genetics, 2012, v. 8, n. 11, p. 1, doi. 10.1371/journal.pgen.1003042
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- Publication type:
- Article
Genetic Modifiers of MeCP2 Function in Drosophila.
- Published in:
- PLoS Genetics, 2008, v. 4, n. 9, p. 1, doi. 10.1371/journal.pgen.1000179
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- Publication type:
- Article
dAtaxin-2 Mediates Expanded Ataxin-1-Induced Neurodegeneration in a Drosophila Model of SCA1.
- Published in:
- PLoS Genetics, 2007, v. 3, n. 12, p. e234, doi. 10.1371/journal.pgen.0030234
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- Publication type:
- Article
Huntingtin Interacting Proteins Are Genetic Modifiers of Neurodegeneration.
- Published in:
- PLoS Genetics, 2007, v. 3, n. 5, p. e82, doi. 10.1371/journal.pgen.0030082
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- Publication type:
- Article
Comparative analysis of genetic modifiers in Drosophila points to common and distinct mechanisms of pathogenesis among polyglutamine diseases.
- Published in:
- Human Molecular Genetics, 2008, v. 17, n. 3, p. 376, doi. 10.1093/hmg/ddm315
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- Publication type:
- Article