We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
HIF1A Reduces Acute Lung Injury by Optimizing Carbohydrate Metabolism in the Alveolar Epithelium.
- Authors
Eckle, Tobias; Brodsky, Kelley; Bonney, Megan; Packard, Thomas; Han, Jun; Borchers, Christoph H.; Mariani, Thomas J.; Kominsky, Douglas J.; Mittelbronn, Michel; Eltzschig, Holger K.
- Abstract
: A study of acute lung injury reveals the involvement of transcription factor HIF1A in lung protection, where normoxic HIF1A stabilization functions to control alveolar epithelial glucose metabolism.
- Subjects
HYPOXIA-inducible factor 1; LUNG injury treatment; GLUCOSE metabolism; ARTIFICIAL respiration; LUNG physiology; PNEUMONIA treatment
- Publication
PLoS Biology, 2013, Vol 11, Issue 9, p1
- ISSN
1544-9173
- Publication type
Article
- DOI
10.1371/journal.pbio.1001665