(6a R)-1,2-(Methylenedioxy)aporphine-10, 11-diol ( 8) and (6a R)-aporphine-1, 1, 10, 11-tetrol ( 16) have been prepared from natural ( S)-bulbocapnine ( 4). For both compounds, the partial synthesis included racemic intermediates which have been resolved into their enantiomers. Both compounds 8 and 16 showed dopaminergic activity in rats, although to a lower extent than ( R)-apomorphine ( 1) itself.