We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Enhanced astaxanthin production from microalga, Haematococcus pluvialis by two-stage perfusion culture with stepwise light irradiation.
- Authors
Park, Joon; Choi, Seung; Hong, Min-Eui; Sim, Sang
- Abstract
For efficient astaxanthin production from the culture of green microalga, Haematococcus pluvialis, a two-stage mixotrophic culture system was established with stepwise increased light irradiance. By perfusion process, high density biomass (2.47 g/L) was achieved during the vegetative stage due to no detrimental effect of inhibitory metabolites, which was 3.09 and 1.67 times higher than batch and fed-batch processes, respectively. During the induction stage, biomass and astaxanthin were subsequently produced to the very high level 12.3 g/L and 602 mg/L, under stepwise increased light irradiance (150-450 μE/m/s), respectively. These results indicate that the combinatorial approach of perfusion culture during the vegetative stage and stepwise light irradiation during the induction stage is a promising strategy for the simultaneous production of high concentration of biomass and astaxanthin in microalgae including H. pluvialis.
- Subjects
ASTAXANTHIN; MICROALGAE cultures &; culture media; BIOMASS production; ALGAL metabolites; BATCH reactors; COMBINATORICS
- Publication
Bioprocess & Biosystems Engineering, 2014, Vol 37, Issue 10, p2039
- ISSN
1615-7591
- Publication type
Article
- DOI
10.1007/s00449-014-1180-y