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- Title
Conversion of HPLC method to UPLC method for determination of preservatives in cosmetics.
- Authors
LV Gao-hao; DENG Xiu-ying; ZHU Si-yang; LONG Yong-an; WEN Cai-ling; ZENG Hao-ji; GAN Rui-jie
- Abstract
In recent years, more and more attention has been paid on ultra-performance liquid chromatography(HPLC). In this work, based on the method in the Technical Specification for Safety of Cosmetics (2021 Edition) for analysis of preservatives, an ultraperformance liquid chromatography method for the analysis of preservatives in cosmetics was established. The difference between HPLC and UPLC was compared and the UPLC method was verified to ensure the accuracy and effectiveness of the method after conversion. The experimental results show that, the method has high accuracy, precision, repeatability and sensitivity and can meet the requirements of the actual standard for the detection of 8 preservatives such as benzyl alcohol, which can provide new technical support for laboratory detection.
- Publication
Detergent & Cosmetics, 2023, Vol 46, Issue 2, p24
- ISSN
1006-7264
- Publication type
Article
- DOI
10.3969/j.issn.1006-7264.2023.02.005