We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Metabolomic and Proteomic Profiling of Athletes Performing Physical Activity under Hypoxic Conditions.
- Authors
Malsagova, Kristina A.; Kopylov, Arthur T.; Stepanov, Alexander A.; Kulikova, Liudmila I.; Izotov, Alexander A.; Yurku, Ksenia A.; Balakin, Evgenii I.; Pustovoyt, Vasiliy I.; Kaysheva, Anna L.
- Abstract
Proteomic and metabolomic research enables quantitation of the molecular profile of athletes. Multiomic profiling was conducted using plasma samples collected from 18 male athletes performing aerobic activity (running) at high altitude. Metabolomic profiling detected changes in the levels of 4-hydroxyproline, methionine, oxaloacetate, and tyrosine during the recovery period. Furthermore, proteomic profiling revealed changes in expression of proteins contributing to the function of the immune system, muscle damage, metabolic fitness and performance, as well as hemostasis. Further research should focus on developing metabolic models to monitor training intensity and athlete adaptation.
- Subjects
PHYSICAL activity; PROTEOMICS; METABOLOMICS; MALE athletes; PROTEIN expression
- Publication
Sports (2075-4663), 2024, Vol 12, Issue 3, p72
- ISSN
2075-4663
- Publication type
Article
- DOI
10.3390/sports12030072