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- Title
Effectiveness of Pulmonary Rehabilitation among COVID-19 Patients: A Systematic Review and Meta-Analysis.
- Authors
AL-Mhanna, Sameer Badri; Mohamed, Mahaneem; Noor, Norhayati Mohd; Afolabi, Hafeez Abiola; Irekeola, Ahmad Adebayo; Bello, Kizito Eneye; Aldhahi, Monira I.; Wan Ghazali, Wan Syaheedah
- Abstract
Background: Many COVID-19 patients presented with detrimental features, such as impaired respiratory function, physical capacity, and overall poor quality of life. The present study evaluates the effectiveness of pulmonary rehabilitation on COVID-19 patients. Methods: We searched PubMed, Scopus, ScienceDirect, and Google Scholar from 2019 to 2021. The protocol was registered in PROSPERO with the registration number CRD42021273618. We performed statistical analyses via random effects and expressed the outcomes as standardized mean difference (SMD) for continuous variables, with 95% confidence intervals (CI). Results: We included six trials involving 432 patients. The primary outcome showed a significant improvement in physical function (SMD 0.83, 95% CI −0.58 to 1.09; p < 0.001; four trials, 266 participants; high-quality evidence). There was significant difference in anxiety (SMD −0.80, 95% CI −1.23 to −0.37; p = 0.003), physical activity intensity levels (SMD −1.27, 95% CI −2.23 to −0.32; p = 0.009), sleep quality (MD −0.05, 95% CI −0.83 to −0.16; p = 0.004), peripheral muscle performance of lower limbs (SMD 0.90, 95% CI −0.60 to 1.20; p < 0.001), and dyspnoea outcomes (SMD −0.55, 95% CI −0.87 to −0.23; p = 0.007). Conclusions: Pulmonary rehabilitation is an effective adjuvant therapy that minimizes COVID-19 severity in the intervention group compared to the conventional treatment. The findings of this study will need to be considered in the framework of the clinical outcome as observed in the intervention outcome. Additionally, safer data on guideline rehabilitation would be needed to examine whether pulmonary rehabilitation would be a fruitful intervention to reduce COVID-19 severity.
- Subjects
SKELETAL muscle physiology; LUNG physiology; ANXIETY prevention; MEDICAL rehabilitation; ONLINE information services; COVID-19; META-analysis; LUNG diseases; SYSTEMATIC reviews; FUNCTIONAL status; TREATMENT effectiveness; PHYSICAL activity; BODY movement; MEDLINE; EVALUATION
- Publication
Healthcare (2227-9032), 2022, Vol 10, Issue 11, p2130
- ISSN
2227-9032
- Publication type
Article
- DOI
10.3390/healthcare10112130