We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
苍砂白芥汤联合平消胶囊对子宫肌瘤患者T 淋巴细胞亚群、 性激素水平和子宫动脉血流指数的影响.
- Authors
马静毅; 蔡丹磊; 刘颖; 李娟; 王薇
- Abstract
Objective: To explore the effects of Cangsha Baijie decoction and Pingxiao capsule on T-lymphocyte subgroup, sex hormone level and uterine artery blood flow index in patients with hysteromyoma. Methods: 90 patients with hysteromyoma who were admitted to our hospital from December 2018 to December 2019 were selected as the study subjects. The patients were divided into control group (30 cases, treated with mifepristone tablets), observation group 1 (30 cases, treated with mifepristone tablets, Pingxiao capsule) and observation group 2 (30 cases, treated with mifepristone tablets, Cangsha Baijie decoction, Pingxiao capsule) by random number table method and random remainder grouping method. 3 months after treatment, the clinical efficacy, myoma volume, T lymphocyte subsets, sex hormone levels, uterine artery blood flow index and adverse reactions of the three groups were compared. Results: The total clinical effective rate was 96.67% in the observation group 2, 86.67% in the observation group 1 and 70.00% in the control group. There was significant difference in the three groups (P<0.05). 3 months after treatment, The levels of follicle stimulating hormone (FSH), progesterone (P), estradiol (E2) were lower than those before treatment, the observation group 2 were lower than those in the observation group 1, the observation group 1 was lower than those in the the control group. The resistance index (RI) and pulsation index (PI) of uterine artery in the observation group 2 were better than those in the observation group 1 and the control group, the differences were significant (P<0.05). 3 months after treatment, the levels of CD3+, CD4+ and CD4+/CD8+ in the three groups were significantly higher than those before treatment, the level of CD8+ was significantly lower than that before treatment. The levels of CD3+, CD4+ and CD4+/CD8+ in observation group 1 and observation group 2 were higher than those in control group, while the levels of CD8+ in observation group 1 and observation group 2 were lower than those in control group, the differences were significant (P<0.05). There was no significant difference in the incidence of adverse reactions among the three groups. Cangsha Baijie decoction combined with Pingxiao capsule can improve the therapeutic effect, T lymphocyte subsets, sex hormone level and uterine artery blood flow index of patients with hysteromyoma, without increasing adverse drug reactions.
- Subjects
LYMPHOCYTE subsets; DRUG side effects; UTERINE artery; T cells; TREATMENT effectiveness
- Publication
Progress in Modern Biomedicine, 2020, Vol 20, Issue 15, p2957
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2020.15.032