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- Title
Rapid malignant transformation of an intracranial epidermoid cyst: Report of a case.
- Authors
Narasimhaiah, Deepti; Nair, Prakash; Kesavadas, Chandran; Poyuran, Rajalakshmi
- Abstract
Intracranial epidermoid cysts (ECs) occur at various locations along the neuraxis and account for nearly 2% of all intracranial tumors. Considering the frequency of ECs, transformation of ECs into squamous cell carcinomas is a rare occurrence. Here, we report the case of a 39‐year‐old man who presented with a lesion in the left cerebellopontine angle and underwent gross total resection for the same. Histopathological examination revealed a benign EC with mild chronic inflammation. Five months later, the patient presented with another lesion at the same location with evidence of brainstem bleed. Histopathological examination revealed a moderately differentiated squamous cell carcinoma and remnants of the previous cyst in the form of lamellated keratin, indicating malignant transformation of the EC.
- Subjects
CEREBELLOPONTILE angle; EPIDERMAL cyst; SQUAMOUS cell carcinoma; INTRACRANIAL tumors; KERATIN; HISTOPATHOLOGY
- Publication
Neuropathology, 2023, Vol 43, Issue 3, p268
- ISSN
0919-6544
- Publication type
Article
- DOI
10.1111/neup.12884