We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Chemical Elicitors of Antibiotic Biosynthesis in Actinomycetes.
- Authors
Tyurin, Anton P.; Alferova, Vera A.; Korshun, Vladimir A.
- Abstract
Whole genome sequencing of actinomycetes has uncovered a new immense realm of microbial chemistry and biology. Most biosynthetic gene clusters present in genomes were found to remain “silent” under standard cultivation conditions. Some small molecules—chemical elicitors—can be used to induce the biosynthesis of antibiotics in actinobacteria and to expand the chemical diversity of secondary metabolites. Here, we outline a brief account of the basic principles of the search for regulators of this type and their application.
- Subjects
ELICITORS (Botany); BIOSYNTHESIS; ANTIBIOTICS manufacturing; MICROBIOLOGICAL chemistry; ACTINOMYCETALES
- Publication
Microorganisms, 2018, Vol 6, Issue 2, p52
- ISSN
2076-2607
- Publication type
Article
- DOI
10.3390/microorganisms6020052