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- Title
Molecular Mechanism of Memory Modification.
- Authors
Balaban, P. M.
- Abstract
The present review of our own and published data proposes a hypothesis for the molecular mechanisms regulating synaptic efficiency which may underlie long-term changes in behavior and modification of memory on the reactivation. The hypotheses is based on data on role of the atypical protein kinase molecule Mζ in long-term changes in synaptic efficiency by controlling the delivery of AMPA receptors, and on data on the possible nitrosylation of these molecules by nitric oxide, which is produced in synapses when nerve cells are activated.
- Subjects
NEURONS; NITROSYLATION; NEUROPLASTICITY; PROTEIN kinases; AMPA receptors
- Publication
Neuroscience & Behavioral Physiology, 2018, Vol 48, Issue 6, p734
- ISSN
0097-0549
- Publication type
Article
- DOI
10.1007/s11055-018-0624-2