We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Benefits and Risks of Early Life Iron Supplementation.
- Authors
McMillen, Shasta A.; Dean, Richard; Dihardja, Eileen; Ji, Peng; Lönnerdal, Bo
- Abstract
Infants are frequently supplemented with iron to prevent iron deficiency, but iron supplements may have adverse effects on infant health. Although iron supplements can be highly effective at improving iron status and preventing iron deficiency anemia, iron may adversely affect growth and development, and may increase risk for certain infections. Several reviews exist in this area; however, none has fully summarized all reported outcomes of iron supplementation during infancy. In this review, we summarize the risks and benefits of iron supplementation as they have been reported in controlled studies and in relevant animal models. Additionally, we discuss the mechanisms that may underly beneficial and adverse effects.
- Subjects
THERAPEUTIC use of iron; IRON deficiency anemia prevention; INFECTION risk factors; HUMAN growth; INFANT development; IRON; GUT microbiome; IRON in the body; DIETARY supplements; INFANT nutrition; NEURAL development; OXIDATIVE stress; RISK assessment; EARLY intervention (Education); MINERALS; CHILDREN
- Publication
Nutrients, 2022, Vol 14, Issue 20, p4380
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu14204380