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- Title
Therapeutic siCCR2 Loaded by Tetrahedral Framework DNA Nanorobotics in Therapy for Intracranial Hemorrhage (Adv. Funct. Mater. 33/2021).
- Authors
Fu, Wei; Ma, Lu; Ju, Yan; Xu, Jianguo; Li, Hao; Shi, Sirong; Zhang, Tao; Zhou, Ronghui; Zhu, Jianwei; Xu, Ruxiang; You, Chao; Lin, Yunfeng
- Abstract
Keywords: chemokine receptor 2; intracranial hemorrhage; microglia; siRNA; tFNA EN chemokine receptor 2 intracranial hemorrhage microglia siRNA tFNA 1 1 1 08/19/21 20210816 NES 210816 B Tetrahedral Framework DNA b In article number 2101435, Chao You, Yunfeng Lin, and co-workers design a nanomaterial (tetrahedron framework nucleic acid, tFNA) to carry siCCR2 that could promote hematoma absorption by regulating microglia polarization from the M1 toward M2 subtype during the acute phase of intracranial hemorrhage. Chemokine receptor 2, intracranial hemorrhage, microglia, siRNA, tFNA Therapeutic siCCR2 Loaded by Tetrahedral Framework DNA Nanorobotics in Therapy for Intracranial Hemorrhage (Adv. Funct.
- Subjects
NANOROBOTICS; HEMORRHAGE; DNA; CHEMOKINE receptors
- Publication
Advanced Functional Materials, 2021, Vol 31, Issue 33, p1
- ISSN
1616-301X
- Publication type
Article
- DOI
10.1002/adfm.202170239