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- Title
Adherence to HIV post-exposure prophylaxis in a specialized service in São Paulo, Brazil.
- Authors
Santos Silva, Marcos Morais; Simões Duarte, Luciane; Izumi Nichiata, Lucia Yasuko
- Abstract
Introduction: The effectiveness of human immunodeficiency virus (HIV) post-exposure prophylaxis (PEP) depends on adherence to the protocol, which includes taking antiretrovirals (ARVs) and attending visits. We examined the adherence rate to antiretroviral agents and followup visits identifying the associated characteristics of adherence and the reasons for not attending HIV PEP consultations in a specialized service in São Paulo, Brazil. Methodology: This was a cross-sectional study with health service users who had an indication for PEP due to sexual exposure in an HIV/AIDS service from April to October 2019. The health service users were followed-up throughout the prophylaxis cycle. Adherence was determined through self-reports on antiretroviral agent use and attendance to follow-up consultations. Results: Association measures were employed to identify adherence-related characteristics. The sample analyzed included 91 users. The mean age was 32.5 years old (SD = 9.8). The largest share was white-skinned (49.5%), men who have sex with other men (62.2%), male (86.8%), and undergraduate/graduate students (65.9%). Adherence totaled 56.7% and health insurance was the associated characteristic (p = 0.039). Work (55.9%), using a private service (15.2%), forgetfulness (11.8%) and considering follow-up unnecessary (11.8%) were the main reasons for not attending the follow-up appointments. Conclusions: Few users do attend HIV PEP consultations. The users without health insurance had the highest adherence percentage whereas work was mentioned as a reason for not attending HIV PEP consultations.
- Subjects
SAO Paulo (Brazil); PRE-exposure prophylaxis; HIV; ANTIRETROVIRAL agents
- Publication
Journal of Infection in Developing Countries, 2023, Vol 17, Issue 6, p860
- ISSN
2036-6590
- Publication type
Article
- DOI
10.3855/jidc.17515