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- Title
Mustering the micromanagers.
- Authors
Lim, Lee P.; Linsley, Peter S.
- Abstract
The article provides an overview of the properties and distribution of the microRNA (miRNA) through a study that presents information on its expression in a broad range of cell types from human and rodent samples. The results demonstrated limited regulation of miRNA levels in response to several stimuli. Treatment of HeLa and A549 cells with interferons triggered very little change in miRNA levels, but very large changes in mRNA levels. Results obtained using microarray hybridization methods agreed more with each other than with the clone count analysis.
- Subjects
MESSENGER RNA; ANTISENSE RNA; GENETIC regulation; GENE expression; HELA cells; CLONE cells; CELL fusion; INTERFERONS; BIOTECHNOLOGY
- Publication
Nature Biotechnology, 2007, Vol 25, Issue 9, p996
- ISSN
1087-0156
- Publication type
Article
- DOI
10.1038/nbt0907-996