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- Title
Genetically Determined Phenotype Covariation Networks Control Bone Strength.
- Authors
Jepsen, Karl J.; Courtland, Hayden-William; Nadeau, Joseph H.
- Abstract
The article describes a study which examined how genetic variants regulate components of a phenotypic covariation network that characterize the compensatory trait interactions involved in functional adaptation during growth. Results show that variation in morphologic compensation and tissue quality determined femoral strength relative to body weight. The study also proves that the genetically determined phenotype covariation networks control bone strength.
- Subjects
BONES; GENETICS; PHENOTYPES; MORPHOLOGY; BODY weight
- Publication
Journal of Bone & Mineral Research, 2010, Vol 25, Issue 7, p1581
- ISSN
0884-0431
- Publication type
Article
- DOI
10.1002/jbmr.41