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- Title
Gastrointestinal Manifestations in Systemic Autoimmune Diseases.
- Authors
Cojocaru, M.; Cojocaru, Inimioara Mihaela; Silosi, Isabela; Vrabie, Camelia Doina
- Abstract
In an autoimmune disease, the immune system attacks and harms the body's own tissues. The systemic autoimmune diseases include collagen vascular diseases, the systemic vasculitides, Wegener granulomatosis, and Churg-Strauss syndrome. These disorders can involve any part of the gastrointestinal tract, hepatobiliary system and pancreas. They can cause a variety of gastrointestinal manifestations that are influenced by the pathophysiologic characteristics of the underlying disease process. There is a wide variation of gastrointestinal manifestations from these autoimmune disorders including, but not limited to: oral ulcers, dysphagia, gastroesophageal reflux disease, abdominal pain, constipation, diarrhea, fecal incontinence, pseudo-obstruction, perforation and gastrointestinal bleeding. Clinical workup should be initiated by the patient's subjective complaints. In this review, we analyze the effects of autoimmune diseases on the gastrointestinal tract.
- Subjects
AUTOIMMUNE diseases; COLLAGEN diseases; VASCULITIS; GRANULOMATOSIS with polyangiitis; CHURG-Strauss syndrome
- Publication
Maedica - a Journal of Clinical Medicine, 2011, Vol 6, Issue 1, p45
- ISSN
1841-9038
- Publication type
Article