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- Title
Response to Correspondence to "Short‐course subcutaneous treatment with PQ Grass strongly improves symptom and medication scores in grass allergy".
- Authors
de Kam, P. J.; Zielen, S.; Bernstein, J. A.; Berger, U.; Berger, M.; Cuevas, M.; Cypcar, D.; Fuhr‐Horst, A.; Greisner, W. A.; Jandl, M.; Laßmann, S.; Worm, M.; Matz, J.; Sher, E.; Smith, C.; Steven, G. C.; Mösges, R.; Shamji, M. H.; DuBuske, L.; Borghese, F.
- Abstract
This document is a response to concerns raised by Cheng et al. regarding a previous paper on the short-term efficacy of pre-seasonal subcutaneous administration of PQ Grass for grass allergy. The authors acknowledge the importance of long-term efficacy and safety and state that separate Phase III studies will address these aspects. They also address concerns about adverse events (AEs) by highlighting the extensive safety monitoring procedures implemented during the study. Additionally, the authors mention that underlying immunological mechanisms were evaluated through biomarker analysis, with findings indicating immune tolerance induction by PQ Grass AIT. The document concludes by acknowledging the contributions of individuals involved in editing and publishing the manuscript and disclosing conflicts of interest.
- Subjects
MONONUCLEAR leukocytes; ALLERGIES
- Publication
Allergy, 2024, Vol 79, Issue 6, p1637
- ISSN
0105-4538
- Publication type
Article
- DOI
10.1111/all.16104