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Title
Identification of Dep-1, a new gene regulated by the transcription factor Pax-3, as a marker for altered embryonic gene expression during diabetic pregnancy.
Examines the causes of diabetic embryopathy in which congenital malformations arise in the early developing embryo of a pregnant mother with preexisting diabetes. Abnormal expression of important regulatory genes in the embryo; Ability to detect Dep-1 RNA in uninduced P19 cells.