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- Title
Of Molecules and Mechanisms.
- Authors
Benson, Deanna L.
- Abstract
Without question, molecular biology drives modern neuroscience. The past 50 years has been nothing short of revolutionary as key findings have moved the field from correlation toward causation. Most obvious are the discoveries and strategies that have been used to build tools for visualizing circuits, measuring activity, and regulating behavior. Less flashy, but arguably as important are the myriad investigations uncovering the actions of single molecules, macromolecular structures, and integrated machines that serve as the basis for constructing cellular and signaling pathways identified in wide-scale gene or RNA studies and for feeding data into informational networks used in systems biology. This review follows the pathways that were opened in neuroscience by major discoveries and set the stage for the next 50 years.
- Subjects
SINGLE molecules; MOLECULAR biology; SYSTEMS biology; MOLECULES; MACROMOLECULAR synthesis; NEUROSCIENCES
- Publication
Journal of Neuroscience, 2020, Vol 40, Issue 1, p81
- ISSN
0270-6474
- Publication type
Article
- DOI
10.1523/JNEUROSCI.0743-19.2019