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- Title
Accuracy of real-time shear wave elastography in staging hepatic fibrosis: a meta-analysis.
- Authors
Fu, Juan; Wu, Biao; Wu, Huazhi; Lin, Feng; Deng, Wei
- Abstract
Background: Chronic liver disease (CLD) is an important cause of morbidity and mortality and can lead to hepatic fibrosis. This study was conducted to evaluate the diagnostic value of real-time shear wave elastography (SWE) in the assessment of hepatic fibrosis. Methods: A systematic search of databases was performed for publications on SWE during the period between 2010 and 2017. The identified studies were analyzed using Meta-disc 1.4 software to integrate and analyze the data. Results: Eleven studies comprising 1560 patients were included for analysis. The pooled sensitivity, specificity and diagnostic odds ratio were 0.85 (95% CI: 0.82–0.87), 0.79 (95% CI: 0.76–0.82) and 30.81 (95% CI: 16.55–57.34), respectively for patients with a Metavir-score of ≥ F2; 0.87 (95% CI: 0.84–0.91), 0.84 (95% CI: 0.82–0.87), 41.45 (95% CI:18.25–94.45), respectively for patients with ≥ F3; 0.88(95% CI: 0.83–0.91), 0.91 (95% CI: 0.89–0.92), 67.18 (95% CI:30.02–150.31), respectively for patients with ≥ F4. The areas under the receiver operating characteristic curve of the three groups were 0.9147, 0.9223 and 0.9520, respectively. Conclusions: Our work demonstrates that SWE is highly accurate for detecting and staging hepatic fibrosis.
- Subjects
HEPATIC fibrosis; SHEAR waves; RECEIVER operating characteristic curves; META-analysis; ELASTOGRAPHY
- Publication
BMC Medical Imaging, 2020, Vol 20, Issue 1, p1
- ISSN
1471-2342
- Publication type
Article
- DOI
10.1186/s12880-020-0414-5