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- Title
Response to: topical cyclosporine A 0.05% before and after surgery to prevent pterygium recurrence.
- Authors
Fernandes de Sousa Meneghim, Roberta Lilian; Horikawa Satto, Larissa; Leiko Natsuaki, Kryscia; Carvalho de Oliveira, Alessandro; Roberto Padovani, Carlos; Hata Viveiros, Magda Massae; Artioli Schellini, Silvana
- Abstract
The article discusses risk factor of pterygium progression remains ultraviolet exposure, and challenging aspects involving lesion is the prevention of recurrence. Topics include CsA is effective in inhibiting fibroblast proliferation, both in primary and in recurrent pterygium; and combination of CsA with bevacizumab can reduce fibroblast outgrowth from cultured pterygium tissue explants, playing an important role in fibroblast migration and preventing T-helper cell activation.
- Subjects
PTERYGIUM; CYCLOSPORINE; OPERATIVE surgery; MEDICAL schools; CONFLICT of interests; FIBROBLASTS
- Publication
Arquivos Brasileiros de Oftalmologia, 2022, Vol 85, Issue 2, p203
- ISSN
0004-2749
- Publication type
Article