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- Title
Is cholesterol a conditionally essential nutrient in critically ill patients?
- Authors
Druml, Wilfred
- Abstract
Cholesterol has such a low reputation in modern medicine that it is frequently overlooked what a broad spectrum of important physiologic functions it has to fulfil. However, Cholesterol has a crucial role in membrane composition and function. Cholesterol and phospholipids are the principal constituents of biological membranes, the cholesterollphospholipid molar ratio being the main factor that determines the microviscosity of lipid regions. The potential mechanisms leading to hypocholesterolemia in the critically ill are poorly understood. The main cause certainly, is reduced endogenous cholesterol production.
- Subjects
CHOLESTEROL; PHOSPHOLIPIDS; BIOLOGICAL membranes; HYPOCHOLESTEREMIA; CRITICAL care medicine; ISOPENTENOIDS
- Publication
Wiener Klinische Wochenschrift, 2003, Vol 115, Issue 21/22, p740
- ISSN
0043-5325
- Publication type
Editorial
- DOI
10.1007/BF03040497