We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Modulation of Oxidative Stress and Hemostasis by Flavonoids from Lentil Aerial Parts.
- Authors
Żuchowski, Jerzy; Rolnik, Agata; Adach, Weronika; Stochmal, Anna; Olas, Beata; Rupasinghe, H.P. Vasantha
- Abstract
While specific metabolites of lentil (Lens culinaris L.) seeds and their biological activity have been well described, other organs of this plant have attracted little scientific attention. In recent years, green parts of lentils have been shown to contain diverse acylated flavonoids. This work presents the results of the research on the effect of the crude extract, the phenolic fraction, and seven flavonoids obtained from aerial parts of lentils on oxidative damage induced by H2O2/Fe to lipid and protein constituents of human plasma. Another goal was to determine their effect on hemostasis parameters of human plasma in vitro. Most of the purified lentil flavonoids had antioxidant and anticoagulant properties. The crude extract and the phenolic fraction of lentil aerial parts showed antioxidant activity, only at the highest tested concentration (50 μg/mL). Our results indicate that aerial parts of lentils may be recommended as a source of bioactive substances.
- Subjects
LENTILS; OXIDATIVE stress; FLAVONOIDS; HEMOSTASIS; SEEDS
- Publication
Molecules, 2021, Vol 26, Issue 2, p497
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules26020497