We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Haemorrhage following Pancreaticoduodenectomy: Risk Factors and the Importance of Sentinel Bleed.
- Authors
Koukoutsis, I.; Bellagamba, R.; Morris-Stiff, G.; Wickremesekera, S.; Coldham, C.; Wigmore, S. J.; Mayer, A. D.; Mirza, D. F.; Buckels, J. A. C.; Bramhall, S. R.
- Abstract
Aim: To document the prevalence and to evaluate the management strategies of haemorrhagic complications following pancreaticoduodenectomy (PD). Methods: All patients who underwent PD from 1/2000 to 10/2005 and experienced at least one episode of haemorrhage during the 30 first days postoperatively were recorded. Etiology of haemorrhage, treatment strategy and mortality rate were recorded and analyzed. Results: A total of 362 patients underwent PD during this period and 32 (8.8%) had haemorrhage postoperatively of whom 15 died (47% mortality rate). Primary intraluminal haemorrhage was recorded in 13 patients, primary intra-abdominal haemorrhage in 5 patients and secondary haemorrhage in 14 patients. Successful management of haemorrhage with angioembilization occurred in 2 patients in the study group. Statistical analysis revealed sepsis and sentinel bleed as risk factors for post-PD haemorrhage and pancreatic leak and sentinel bleed as risk factors for secondary haemorrhage (p < 0.05). Conclusions: Haemorrhage after PD is a life-threatening complication. Sepsis, pancreatic leak, and sentinel bleed are statistical significant factors predicting post-PD haemorrhage. Sentinel bleed is not statistically significant associated with postoperative mortality, but with the onset of secondary haemorrhage. The effectiveness of therapeutic angioembolization was not demonstrated in our study. Copyright © 2006 S. Karger AG, Basel
- Subjects
PANCREATICODUODENECTOMY; DISEASE complications; SEPSIS; BLOOD diseases; BIOINDICATORS
- Publication
Digestive Surgery, 2006, Vol 23, Issue 4, p224
- ISSN
0253-4886
- Publication type
Article
- DOI
10.1159/000094754