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- Title
Study of effect of amiodarone in CABG.
- Authors
Metta, Vipul; Geelani, Mohammed Abid; Hussain Naqvi, Sayyed Ehtesham; Sharma, Rakesh; Daniel, Sneha
- Abstract
Atrial fibrillation is the most common postoperative complication adding significantly to the morbidity rate and cost of coronary artery bypass surgery (CABG). AF is a superventricular tachyarrhythmia diagnosed through irregular atrial activities and disappearance of atria mechanical function. In electrocardiogram (EGG), AF appears as quick vibrating waves replaced by P-waves and often accompanied by quick and irregular ventricular response. AF may occur in isolation or along with other arrhythmias. Incidence of atrial fibrillation after CABG is between 20% and 40%. This arrhythmia is often benign and transient, but can cause hemodynamic disorders, thromboembolic complications, longer time of hospital stay and serious complications including cerebral apoplexy, and increase in the length of hospitalization. Digoxin, calcium blockers, magnesium, glucose-insulin, potassium solution, and various cardioplegia are ineffective at preventing atrial fibrillation after CABG.Amiodarone is a multifaceted antiarrhythmic with a proven record of effectiveness in the treatment of atrial arrhythmias in a variety of clinical settings. Daud et al showed a significant reduction in postoperative atrial fibrillation with oral amiodarone in patients undergoing either CABG or valvular surgery. In this current study we evaluated the effects of amiodarone in preventing intra and post op arrhythmias and compared it to subjects not receiving amiodarone preoperatively.
- Subjects
ARRHYTHMIA; TACHYARRHYTHMIAS; ATRIAL arrhythmias; CORONARY artery surgery; CORONARY artery bypass; AMIODARONE; CALCIUM antagonists
- Publication
Indian Journal of Basic & Applied Medical Research, 2023, Vol 13, Issue 1, p5
- ISSN
2250-284X
- Publication type
Article
- DOI
10.36855/IJBAMR/2022/000215.622