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- Title
Control of mitochondrial motility and distribution by the calcium signal: a homeostatic circuit.
- Authors
Muqing Yi; Weaver, David; Hajnóczky, György
- Abstract
This article presents a study related to control of mitochondrial motility and distribution by the calcium signal. Distribution of mitochondria to strategic sites is likely to be established by a cytoskeleton-based transportation system. Mitochondria have been visualized in association with the microfilaments, microtubules, and intermediate filaments in various cell types. Mitochondria-bound molecular motors provide a means for the organelles to move along the cytoskeletal fibers. Mitochondrial movements may also increase the chance of dynamic interactions between discrete organelles and may aid the transport of molecules between the cytoplasm and mitochondria.
- Subjects
MITOCHONDRIA; CYTOPLASM; CALCIUM; MICROTUBULES; MOLECULES; CELLS
- Publication
Journal of Cell Biology, 2004, Vol 167, Issue 4, p661
- ISSN
0021-9525
- Publication type
Article
- DOI
10.1083/jcb.200406038