We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Prognostic factors in trabeculectomy with mitomycin C having history of previous glaucoma surgery.
- Authors
Awai-Kasaoka, Nanako; Inoue, Toshihiro; Inatani, Masaru; Takihara, Yuji; Ogata-Iwao, Minako; Tanihara, Hidenobu
- Abstract
Purpose: To evaluate the prognostic factors for surgical outcomes of subsequent trabeculectomy with mitomycin C (MMC) after prior incisional glaucoma surgery. Methods: We reviewed medical records of a total cohort of 781 trabeculectomies with MMC, and selected 125 patients (125 eyes). The primary endpoints included persistent intraocular pressure (IOP) of ≥21 or <5 mmHg, the need for additional glaucoma surgery and deterioration of visual acuity to no light perception. Univariate and Multivariate analyses were performed by using the Cox proportional hazards model. Results: The mean follow-up period was 26.8 months. The probabilities of success at 1, 2, and 3 years were 80.6, 72.2, and 70.6 %, respectively. Multivariate analysis showed that a shorter time interval between prior glaucoma surgery and subsequent trabeculectomy [relative risk (RR), 0.8867/year; P = 0.0090] and the number of prior trabeculectomies (RR, 2.2645; P = 0.0029) were significant prognostic factors for subsequent failure of trabeculectomy with MMC. Conclusion: A short time period between prior glaucoma surgery and subsequent trabeculectomy and the number of prior trabeculectomies are associated with surgical failure of subsequent trabeculectomy with MMC.
- Subjects
GLAUCOMA surgery; MITOMYCIN C; INTRAOCULAR pressure; REOPERATION; PREOPERATIVE risk factors; MEDICAL records
- Publication
Japanese Journal of Ophthalmology, 2013, Vol 57, Issue 6, p514
- ISSN
0021-5155
- Publication type
Article
- DOI
10.1007/s10384-013-0257-5