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- Title
The Anti-depressant Activity of Fixed Oil of Phaseolus vulgaris Linn. in Mice.
- Authors
Sabir, Salma; Baig, Sadia Ghousia; Hasan, Muhammad Mohtasheem ul; Siddiq, Afshan; Ahmed, Salman; Fatima, Syeda Anum
- Abstract
Phaseolus vulgaris Linn commonly known as red kidney bean, it is enriched in protein, carbohydrates and dietary fibres. Beans have nutritional and health benefits and also possess antimicrobial, antihyperglycemic, antioxidant and anticancer activity due to presence of bio-active chemical constituents. The following study was carried out to evaluate the anti-depressant activity of Phaseolus vulgaris fixed oil (PVFO) using forced swim test and tail suspension test in mice. In this study animals assigned into four groups (n=7). Group I: Control normal saline (2 mL/Kg), Group II: PVFO I (2 mL/Kg), Group III: PVFO II (4 mL/Kg) and Group IV: standard amitriptyline (10 mg/Kg). The results were significant and indicated the possible anti-depressant role of Phaseolus vulgaris fixed oil.
- Subjects
KIDNEY bean; COMMON bean; MICE; BEANS; AMITRIPTYLINE; CARBOHYDRATES
- Publication
Pakistan Journal of Scientific & Industrial Research Series A: Physical Sciences, 2021, Vol 64, Issue 1, p1
- ISSN
2221-6413
- Publication type
Article