We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
최근 국내에서 유행하는 돼지 유행성 설사 바이러스 nucleocapsid 유전자의 다양성 및 계통 분석
- Authors
김기주; 박유경; 박보경; 람쯩꽝; 박소연; 김재훈; 한태욱
- Abstract
Porcine epidemic diarrhea virus (PEDV), a porcine enteropathogenic coronavirus, causes lethal watery diarrhea in piglets, resulting in large economic losses because of high mortality. In November 2013, PEDV reemerged in Korea, and these outbreaks have since continuously occurred. In the present study, we determined the full-length nucleocapsid (N) gene sequences of three Korean PEDV field isolates collected in 2014-2015. Sequence and phylogenetic analysis of N genes revealed that recent prevalent Korean PEDV isolates were very closely related to the US PEDV isolates in 2013. Interestingly, the phylogenetic tree based on the nucleotide sequencing of the PEDV N gene was similar to the tree topology of the PEDV complete genomes. Therefore, our data provide a better understanding of the genetic diversity and contribute to the accurate diagnosis and development of vaccines against PEDV.
- Publication
Korean Journal of Veterinary Research, 2016, Vol 56, Issue 1, p23
- ISSN
2466-1384
- Publication type
Article
- DOI
10.14405/kjvr.2016.56.1.23