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- Title
Acute encephalopathy associated with influenza A infection in adults.
- Authors
Lee N; Wong CK; Chan PK; Lindegardh N; White NJ; Hayden FG; Wong EH; Wong KS; Cockram CS; Sung JJ; Hui DS; Lee, Nelson; Wong, Chun Kwok; Chan, Paul K S; Lindegardh, Niklas; White, Nicholas J; Hayden, Frederick G; Wong, Edward H C; Wong, Ka Shing; Cockram, Clive S
- Abstract
We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios > or =3), and interleukin-6, CXCL10/IP-10, but no evidence of viral neuroinvasion. Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis.
- Publication
Emerging Infectious Diseases, 2010, Vol 16, Issue 1, p139
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid1601.090007