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- Title
Population-based review of tetralogy of Fallot with absent pulmonary valve: is prenatal diagnosis really associated with a poor prognosis?
- Authors
MIVELAZ, Y.; LIM, K. I.; TEMPLETON, C.; CAMPBELL, A. I.; POTTS, J. E.; SANDOR, G. G. S.
- Abstract
Objectives Tetralogy of Fallot with absent pulmonary valve syndrome (TETAPV) is reported in obstetric literature to have an extremely poor prognosis. We sought to determine the clinical outcome associated with TETAP V and whether prenatal diagnosis confers a poor prognosis. Methods All cases of TETAPV diagnosed in British Columbia between 1980 and 2009 were reviewed and grouped according to time of diagnosis, either prenatal or postnatal. The groups were compared with respect to mortality, respiratory problems, number of interventions and functional capacity at last follow-up. Results Eight and 11 patients were included in the prenatally and postnatally diagnosed groups, with overall long-term survival of 71% and 82%, respectively. There was no significant difference in mortality, frequency of preoperative intubation, number of interventions or functional capacity between groups. Conclusion From a population~based retrospective analysis of TETAPV cases identified over three decades it is concluded that the prognosis for YE TAP V is better than that previously reported in the obstetric literature. This information should be used to guide prenatal counseling.
- Subjects
TETRALOGY of Fallot; CONGENITAL heart disease; PROGNOSIS; PULMONARY valve diseases; RESPIRATORY diseases
- Publication
Ultrasound in Obstetrics & Gynecology, 2012, Vol 40, Issue 5, p536
- ISSN
0960-7692
- Publication type
Article
- DOI
10.1002/uog.11126