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- Title
Thrombophilia and fetal germinal matrix-intraventricular hemorrhage: does it matter?
- Authors
Ramenghi, L. A.; Fumagalli, M.; Righini, A.; Triulzi, F.; Kustermann, A.; F. Mosca
- Abstract
Germinal matrix-intraventricular hemorrhage (GMH-IVH) in the fetus is very rare and the role of thrombophilia in its pathogenesis is unclear. We report on the prenatal diagnosis by magnetic resonance imaging of GMH-IVH in a 24-week fetus. The newborn presented posthemorrhagic ventriculomegaly and was found to be heterozygous for two thrombophilic patterns, factor V Leiden and methylenetetrahydrofolate reductase mutation. The combination of this hypercoagulable state and prenatal GMH-IVH is discussed together with the opportunity of testing these infants for thrombophilia.
- Subjects
UTERINE hemorrhage; PRENATAL diagnosis; OBSTETRICAL diagnosis; MAGNETIC resonance imaging; OBSTETRICAL research
- Publication
Ultrasound in Obstetrics & Gynecology, 2005, Vol 26, Issue 5, p574
- ISSN
0960-7692
- Publication type
Article
- DOI
10.1002/uog.2586