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- Title
Dimensional changes of the maxillary sinus augmented with a collagenated synthetic bone block or synthetic bone particulates: A pre‐clinical study in rabbits.
- Authors
Song, Young Woo; Rafikov, Komoliddin; Paeng, Kyeong‐Won; Kim, Myong Ji; Cha, Jae‐Kook; Thoma, Daniel S.; Jung, Ronald E.; Jung, Ui‐Won
- Abstract
Objective: To compare the efficacy of a collagenated synthetic bone substitute (C‐SBS) to a particulated synthetic bone substitute (P‐SBS) in volume maintenance and new bone formations in a rabbit sinus model. Materials and Methods: Either C‐SBS or P‐SBS was grafted in both sinuses of 16 rabbits. Four (N = 8) or 12 (N = 8) weeks after the surgery, total augmented volume (TAV) and area (TAA), as well as new bone volume (NBV) and area (NBA), were statistically compared by radiographic and histomorphometric analyses (p <.05). Results: The differences in TAV, NBV, TAA and NBA between C‐SBS and P‐SBS groups at 4 weeks were not statistically significant. The TAV (267.13 ± 62.08 vs. 200.18 ± 40.32 mm3) and NBV (103.26 ± 10.50 vs. 71.10 ± 7.58 mm3) in group C‐SBS were significantly higher than in group P‐SBS at 12 weeks (p <.05). The TAA (19.36 ± 2.88 vs. 14.48 ± 2.08 mm2) and NBA (5.43 ± 1.20 vs. 3.76 ± 0.78 mm2) in group C‐SBS were significantly higher than in group P‐SBS at 12 weeks (p <.05). Conclusions: Collagenated synthetic bone substitute grafted in rabbit sinuses demonstrated more favourable outcomes across all outcome measures compared to P‐SBS at 12 weeks.
- Subjects
ANIMAL experimentation; BONE regeneration; BONE substitutes; COLLAGEN; COMPARATIVE studies; CYTOCHEMISTRY; MAXILLARY sinus; RABBITS; DESCRIPTIVE statistics
- Publication
Journal of Clinical Periodontology, 2020, Vol 47, Issue 11, p1416
- ISSN
0303-6979
- Publication type
Article
- DOI
10.1111/jcpe.13363