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- Title
Pre-diabetes and well-controlled diabetes are not associated with periodontal disease: the SHIP Trend Study.
- Authors
Kowall, Bernd; Holtfreter, Birte; Völzke, Henry; Schipf, Sabine; Mundt, Torsten; Rathmann, Wolfgang; Kocher, Thomas
- Abstract
Aim To examine associations of pre-diabetes and well-controlled diabetes with periodontitis. Materials and Methods The Study of Health in Pomerania ( SHIP)-Trend is a cross-sectional survey in North-Eastern Germany including 3086 participants (49.4% men; age 20-82 years). Clinical attachment loss ( CAL) and periodontal probing depth ( PPD) were assessed applying a random half-mouth protocol. The number of teeth was determined. Pre-diabetes comprised impaired fasting glucose and impaired glucose tolerance. Previously known diabetes was defined as well controlled if glycated haemoglobin (HbA1c) was <7.0%. Participants were categorized as follows: normal glucose tolerance ( NGT), pre-diabetes, newly detected type 2 diabetes (T2 DM), known T2 DM with HbA1c<7.0% and known T2 DM with HbA1c≥7.0%. Results Pre-diabetes was neither associated with mean CAL and PPD in multivariable adjusted linear regression models nor with edentulism ( OR = 1.09 (95%- CI: 0.69-1.71)) and number of teeth ( OR = 0.96 (95%- CI: 0.75-1.22), lowest quartile versus higher quartiles) in logistic regression models. Associations with mean CAL and edentulism were stronger in poorly controlled previously known diabetes than in well-controlled previously known diabetes (for edentulism: OR = 2.19 (95%- CI: 1.18-4.05), and OR = 1.40 (95%- CI: 0.82-2.38), respectively, for comparison with NGT). Conclusions Periodontitis and edentulism were associated with poorly controlled T2 DM, but not with pre-diabetes and well-controlled diabetes.
- Subjects
GERMANY; ACADEMIC medical centers; CONFIDENCE intervals; DIABETES; LONGITUDINAL method; PERIODONTAL disease; PREDIABETIC state; REGRESSION analysis; RESEARCH funding; LOGISTIC regression analysis; INTER-observer reliability; CROSS-sectional method; ODDS ratio
- Publication
Journal of Clinical Periodontology, 2015, Vol 42, Issue 5, p422
- ISSN
0303-6979
- Publication type
Article
- DOI
10.1111/jcpe.12391