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- Title
Screening of Panamanian Plant Extracts for Pesticidal Properties and HPLC-Based Identification of Active Compounds.
- Authors
GULDBRANDSEN, Niels; DE MIERI, Maria; HAMBURGER, Matthias; GUPTA, Mahabir; SEISER, Tobias; WIEBE, Christine; DICKHAUT, Joachim; REINGRUBER, Rüdiger; SORGENFREI, Oliver
- Abstract
A library of 600 taxonomically diverse Panamanian plant extracts was screened for fungicidal, insecticidal, and herbicidal activities. A total of 19 active extracts were submitted to HPLC-based activity profiling, and extracts of Bocconia frutescens, Miconia affinis, Myrcia splendens, Combretum aff. laxum, and Erythroxylum macrophyllum were selected for the isolation of compounds. Chelerythrine (2), macarpine (3), dihydrosanguinarine (5), and arjunolic acid (8) showed moderate-to-good fungicidal activity. Myricetin-3-O-(6''-O-galloyl)-β- galactopyranoside (13) showed moderate insecticidal activity, but no compound with herbicidal activity was identified.
- Subjects
PANAMA; PESTICIDAL plants; GENETIC testing; PLANT extracts; FUNGICIDES; INSECTICIDES; HERBICIDES; HIGH performance liquid chromatography
- Publication
Scientia Pharmaceutica, 2015, Vol 83, Issue 2, p353
- ISSN
0036-8709
- Publication type
Article
- DOI
10.3797/scipharm.1410-10