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- Title
The role of gut microbiota in infectious diseases.
- Authors
Cai, Yongjie; Chen, Lingming; Zhang, Sien; Zeng, Lingchan; Zeng, Gucheng
- Abstract
The intestine, the largest immune organ in the human body, harbors approximately 1013 microorganisms, including bacteria, fungi, viruses, and other unknown microbes. The intestine is a most important crosstalk anatomic structure between the first (the host) and second (the microorganisms) genomes. The imbalance of the intestinal microecology, especially dysbiosis of the composition, structure, and function of gut microbiota, is linked to human diseases. In this review, we investigated the roles and underlying mechanisms of gut microecology in the development, progression, and prognosis of infectious diseases. Furthermore, we discussed potential new strategies of prevention and treatment for infectious diseases based on manipulating the composition, structure, and function of intestinal microorganisms in the future. This article is categorized under:Infectious Diseases > Molecular and Cellular Physiology
- Subjects
MICROBIAL ecology; HUMAN body; PROGNOSIS; ORGANS (Anatomy); PHYSIOLOGY; GUT microbiome
- Publication
WIREs: Mechanisms of Disease, 2022, Vol 14, Issue 4, p1
- ISSN
2692-9368
- Publication type
Article
- DOI
10.1002/wsbm.1551