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- Title
Postprandial Glucose and Insulin Reponses to Moderate-Intensity Aerobic Exercise.
- Authors
Quinn, Laurie; Smith, Don; Watkins, Yashika; Bowen, Phyllis; Stacewicz-Sapuntzakis, Maria; Perisee, Donna; Briller, Joan; Calvin, Donna
- Abstract
We examined the effects of aerobic exercise on postprandial metabolism in obese glucose tolerant and intolerant adults. Subjects included African-American (n=24; 9f; 5m), Caucasian (n=12; 8f; 4m) and Hispanic (n=8; 5f; 3m) adults classified into 3 groups (type 2 diabetes [DM] [n = 13]; impaired glucose tolerance [IGT] [n = 7]; normal glucose tolerance [NGT] [n = 24]) based on oral glucose tolerance tests. Subjects were similar in age (44.5 ± 8.5 years [mean ± SD]); BMI (35.2 … 15.1 (kg/m²); total body fat mass (36.7 ± 6.7 kg); total body lean tissue mass (62.8 ± 11.5 kg); and insulin sensitivity (SI) [3.0 ± 1.6 x 10[sup -4] min[sup -1] ⋅ (µU/ml)]; type 2 DM subjects had lower acute insulin responses to glucose (AIRg) and disposition indexes (DI) than those with NGT (p <0.05). Subjects participated in an exercise (E) and non-exercise (NE) protocol. During the E protocol subjects walked on the treadmill for 30 minutes at 65% V0[sub 2] Max; during the NE protocol subjects rested for 30 minutes. Three standard meals were consumed following exercise/rest; glucose and insulin responses were measured at ½ hour prior and ½ 1, 2 and 3 hours following each meal. Percent changes in insulin and glucose responses from baseline were calculated at each timepoint. The data were analyzed using repeated-measures ANOVA. There were between-group differences in plasma glucose responses (type 2 DM vs. NGT) following breakfast (1, 2 hours); following lunch (type 2 DM vs. IGT) (1 hour); following dinner (1 hour) (p <0.05). In addition, them were within-group interactions (group by exercise) following breakfast (2, 3 hours) and dinner (2, 3 hours) (p < 0.05). There were between-group differences in plasma insulin responses (type 2 DM vs. NGT) immediately following exercise (p < 0.05); following breakfast (type 2 DM vs. NGT; type 2 DM vs. IGT) (½, 1 hours) (p < 0.05). In addition, there was an interaction effect (group by exercise) immediately following exercise (p < 0.04); and an interaction effect (exercise) 30 minutes following exercise. These data suggest that moderate intensity aerobic exercise impacts insulin responses during the early post exercise recovery period; such responses are associated with changes in postprandial glycemic responses throughout the entire day. Further studies will examine the impact of higher exercise intensity and/or greater caloric expenditure on postprandial responses.
- Subjects
AEROBIC exercises; INSULIN; BLOOD sugar; METABOLISM; OVERWEIGHT persons; DIABETES; GLUCOSE tolerance tests; BODY mass index
- Publication
Diabetes, 2007, Vol 56, pA367
- ISSN
0012-1797
- Publication type
Article