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Neuron-specific enolase level is a useful biomarker for distinguishing amyotrophic lateral sclerosis from cervical spondylotic myelopathy.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-02310-2
By:
- Tsukahara, Akihiro;
- Hosokawa, Takafumi;
- Nishioka, Daisuke;
- Kotani, Takuya;
- Ishida, Shimon;
- Takeuchi, Tohru;
- Kimura, Fumiharu;
- Arawaka, Shigeki
Publication type:
Article
A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families.
Published in:
2001
By:
- Athan, Eleni S.;
- Williamson, Jennifer;
- Ciappa, Alejandra;
- Santana, Vincent;
- Romas, Stavra N.;
- Lee, Joseph H.;
- Rondon, Haydee;
- Lantigua, Rafael A.;
- Medrano, Martin;
- Torres, Mayobanex;
- Arawaka, Shigeki;
- Rogaeva, Ekaterina;
- Song, You-Qiang;
- Sato, Christine;
- Kawarai, Toshitaka;
- Fafel, Kimberley C.;
- Boss, Michael A.;
- Seltzer, William K.;
- Stern, Yaakov;
- St. George-Hyslop, Peter
Publication type:
journal article
Spatial Fluctuation of Central Nervous System Lesions in X-linked Charcot-Marie-Tooth Disease with a Novel GJB1 Mutation.
Published in:
Internal Medicine, 2024, v. 63, n. 4, p. 571, doi. 10.2169/internalmedicine.1713-23
By:
- Yukiyo Yoshimoto;
- Shoko Yoshimoto;
- Kensuke Kakiuchi;
- Rumina Miyagawa;
- Shin Ota;
- Takafumi Hosokawa;
- Shimon Ishida;
- Yujiro Higuchi;
- Akihiro Hashiguchi;
- Hiroshi Takashima;
- Shigeki Arawaka
Publication type:
Article
P1-059: Overexpression of human alpha-synuclein in transgenic C. elegans: Effects of pathogenic mutations and phosphorylation
Published in:
2006
By:
- Kuwahara, Tomoki;
- Ren, Changhong;
- Koyama, Akihiko;
- Arawaka, Shigeki;
- Kato, Takeo;
- Mitani, Shohei;
- Iwatsubo, Takeshi
Publication type:
Abstract
P1-059: Overexpression of human alpha-synuclein in transgenic C. elegans: Effects of pathogenic mutations and phosphorylation
Published in:
2006
By:
- Kuwahara, Tomoki;
- Ren, Changhong;
- Koyama, Akihiko;
- Arawaka, Shigeki;
- Kato, Takeo;
- Mitani, Shohei;
- Iwatsubo, Takeshi
Publication type:
Abstract
Sensitive western blotting for detection of endogenous Ser129-phosphorylated α-synuclein in intracellular and extracellular spaces.
Published in:
Scientific Reports, 2015, p. 14211, doi. 10.1038/srep14211
By:
- Sasaki, Asuka;
- Arawaka, Shigeki;
- Sato, Hiroyasu;
- Kato, Takeo
Publication type:
Article
White Matter Hyperintensities as a Risk Factor for Ischemic Stroke in Patients With Systemic Lupus Erythematosus.
Published in:
Frontiers in Neurology, 2021, v. 12, p. 1, doi. 10.3389/fneur.2021.738173
By:
- Sano, Eri;
- Arawaka, Shigeki
Publication type:
Article
Zonisamide Attenuates α-Synuclein Neurotoxicity by an Aggregation-Independent Mechanism in a Rat Model of Familial Parkinson’s Disease.
Published in:
PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0089076
By:
- Arawaka, Shigeki;
- Fukushima, Shingo;
- Sato, Hiroyasu;
- Sasaki, Asuka;
- Koga, Kaori;
- Koyama, Shingo;
- Kato, Takeo
Publication type:
Article
Assessment of clinical factors affecting outcome of myasthenia gravis.
Published in:
Muscle & Nerve, 2021, v. 64, n. 1, p. 90, doi. 10.1002/mus.27247
By:
- Yoshimoto, Yukiyo;
- Ishida, Shimon;
- Hosokawa, Takafumi;
- Arawaka, Shigeki
Publication type:
Article
Clinical characteristics of long-term survival with noninvasive ventilation and factors affecting the transition to invasive ventilation in amyotrophic lateral sclerosis.
Published in:
2018
By:
- Hirose, Takahiko;
- Kimura, Fumiharu;
- Tani, Hiroki;
- Ota, Shin;
- Tsukahara, Akihiro;
- Sano, Eri;
- Shigekiyo, Taro;
- Nakamura, Yoshitsugu;
- Kakiuchi, Kensuke;
- Motoki, Mikiko;
- Unoda, Kiichi;
- Ishida, Simon;
- Nakajima, Hideto;
- Arawaka, Shigeki
Publication type:
journal article
Mechanisms underlying extensive Ser129-phosphorylation in a-synuclein aggregates.
Published in:
Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0452-6
By:
- Shigeki Arawaka;
- Hiroyasu Sato;
- Asuka Sasaki;
- Shingo Koyama;
- Takeo Kato
Publication type:
Article
Risk factors and outcome of hyponatremia in patients with Guillain–Barré syndrome.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-67427-6
By:
- Ogawa, Shoji;
- Hosokawa, Takafumi;
- Hayakawa, Chizuko;
- Sawai, Taiki;
- Kakiuchi, Kensuke;
- Nishioka, Daisuke;
- Yoshimoto, Yukiyo;
- Masuda, Yuichi;
- Nakamura, Yoshitsugu;
- Ota, Shin;
- Arawaka, Shigeki
Publication type:
Article
Efficacy and safety of oral high‐trough level tacrolimus in acute/subacute interstitial pneumonia with dermatomyositis.
Published in:
International Journal of Rheumatic Diseases, 2019, v. 22, n. 2, p. 303, doi. 10.1111/1756-185X.13414
By:
- Suzuka, Takayasu;
- Kotani, Takuya;
- Takeuchi, Tohru;
- Fujiki, Youhei;
- Hata, Kenichiro;
- Yoshida, Shuzo;
- Shoda, Takeshi;
- Makino, Shigeki;
- Arawaka, Shigeki
Publication type:
Article
Efficacy of abatacept tapering therapy for sustained remission in patients with rheumatoid arthritis: Prospective single‐center study.
Published in:
International Journal of Rheumatic Diseases, 2019, v. 22, n. 1, p. 81, doi. 10.1111/1756-185X.13384
By:
- Yoshida, Shuzo;
- Kotani, Takuya;
- Kimura, Yuko;
- Matsumura, Yoko;
- Yoshikawa, Ayaka;
- Tokai, Nao;
- Ozaki, Takuro;
- Nagai, Koji;
- Takeuchi, Toru;
- Makino, Shigeki;
- Arawaka, Shigeki
Publication type:
Article
Potential of Krebs von den Lungen‐6 as a predictor of relapse in interstitial pneumonia with anti‐aminoacyl tRNA synthetase antibodies‐positive dermatomyositis.
Published in:
Clinical Respiratory Journal, 2018, v. 12, n. 7, p. 2235, doi. 10.1111/crj.12797
By:
- Isoda, Kentaro;
- Kotani, Takuya;
- Takeuchi, Tohru;
- Konma, Junichi;
- Ishida, Takaaki;
- Hata, Kenichiro;
- Otani, Kenichiro;
- Fujiwara, Hiroshi;
- Shoda, Takeshi;
- Makino, Shigeki;
- Arawaka, Shigeki
Publication type:
Article
The Role of G-Protein-Coupled Receptor Kinase 5 in Pathogenesis of Sporadic Parkinson’s Disease.
Published in:
Journal of Neuroscience, 2006, v. 26, n. 36, p. 9227, doi. 10.1523/JNEUROSCI.0341-06.2006
By:
- Shigeki Arawaka;
- Manabu Wada;
- Saori Goto;
- Hiroki Karube;
- Masahiro Sakamoto;
- Chang-Hong Ren;
- Shingo Koyama;
- Hikaru Nagasawa;
- Hideki Kimura;
- Toru Kawanami;
- Keiji Kurita;
- Katsushi Tajima;
- Makoto Daimon;
- Masanori Baba;
- Takashi Kido;
- Sachiko Saino;
- Kaoru Goto;
- Hironobu Asao;
- Chihumi Kitanaka;
- Emi Takashita
Publication type:
Article
A novel autoantibody in paraneoplastic sensory-dominant neuropathy.
Published in:
Neuropathology, 1997, v. 17, n. 2, p. 89, doi. 10.1111/j.1440-1789.1997.tb00019.x
By:
- Arawaka, Shigeki;
- Kato, Takeo;
- Kurita, Keiji;
- Daimon, Makoto;
- Matsumoto, Naoya;
- Sasaki, Hideo
Publication type:
Article
Nicastrin binds to membrane-tethered Notch.
Published in:
Nature Cell Biology, 2001, v. 3, n. 8, p. 751, doi. 10.1038/35087069
By:
- Chen, Fusheng;
- Yu, Gang;
- Arawaka, Shigeki;
- Nishimura, Masaki;
- Kawarai, Toshitaka;
- Yu, Haung;
- Tandon, Anurag;
- Supala, Agnes;
- Song, You Qiang;
- Rogaeva, Ekaterina;
- Milman, Paul;
- Sato, Christine;
- Yu, Cong;
- Janus, Christopher;
- Lee, Julie;
- Song, Lixin;
- Zhang, Lili;
- Fraser, Paul E.;
- St George-Hyslop, P. H.
Publication type:
Article
Posterior reversible encephalopathy syndrome with extensive cytotoxic edema after blood transfusion: a case report and literature review.
Published in:
2018
By:
- Nakamura, Yoshitsugu;
- Sugino, Masakazu;
- Tsukahara, Akihiro;
- Nakazawa, Hiroko;
- Yamamoto, Naomune;
- Arawaka, Shigeki
Publication type:
journal article
Exploration of pathomechanism using comprehensive analysis of serum cytokines in polymyositis/dermatomyositis-interstitial lung disease.
Published in:
Rheumatology, 2020, v. 59, n. 2, p. 310, doi. 10.1093/rheumatology/kez301
By:
- Matsuda, Shogo;
- Kotani, Takuya;
- Ishida, Takaaki;
- Fukui, Keisuke;
- Fujiki, Youhei;
- Suzuka, Takayasu;
- Nagai, Koji;
- Hata, Kenichiro;
- Shoda, Takeshi;
- Isoda, Kentaro;
- Ito, Yuri;
- Makino, Shigeki;
- Takeuchi, Tohru;
- Arawaka, Shigeki
Publication type:
Article
Occurrence of cerebral small vessel disease at diagnosis of MPO-ANCA-associated vasculitis.
Published in:
Journal of Neurology, 2019, v. 266, n. 7, p. 1708, doi. 10.1007/s00415-019-09318-9
By:
- Tani, Hiroki;
- Nagai, Koji;
- Hosokawa, Takafumi;
- Hata, Kenichiro;
- Kotani, Takuya;
- Ishida, Shimon;
- Takeuchi, Tohru;
- Arawaka, Shigeki
Publication type:
Article
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and BetaAPP processing.
Published in:
Nature, 2000, v. 407, n. 6800, p. 48, doi. 10.1038/35024009
By:
- Yu, Gang;
- Nishimura, Masaki;
- Arawaka, Shigeki;
- Levitan, Diane;
- Zhang, Lili;
- Tandon, Anurag;
- Song, You-Qiang;
- Rogaeva, Ekaterina;
- Chen, Fusheng;
- Kawarai, Toshitaka;
- Supala, Agnes;
- Levesque, Lyne;
- Yu, Haung;
- Yang, Dun-Sheng;
- Holmes, Erin;
- Milman, Paul;
- Liang, Yan;
- Zhang, Dong Mei;
- Xu, Dong Hong;
- Sato, Christine
Publication type:
Article
Laterality of specific binding ratios on DAT-SPECT for differential diagnosis of degenerative parkinsonian syndromes.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72321-y
By:
- Shigekiyo, Taro;
- Arawaka, Shigeki
Publication type:
Article
A Segmental Copy Number Loss of the SFMBT1 Gene Is a Genetic Risk for Shunt-Responsive, Idiopathic Normal Pressure Hydrocephalus (iNPH): A Case-Control Study.
Published in:
PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0166615
By:
- Sato, Hidenori;
- Takahashi, Yoshimi;
- Kimihira, Luna;
- Iseki, Chifumi;
- Kato, Hajime;
- Suzuki, Yuya;
- Igari, Ryosuke;
- Sato, Hiroyasu;
- Koyama, Shingo;
- Arawaka, Shigeki;
- Kawanami, Toru;
- Miyajima, Masakazu;
- Samejima, Naoyuki;
- Sato, Shinya;
- Kameda, Masahiro;
- Yamada, Shinya;
- Kita, Daisuke;
- Kaijima, Mitsunobu;
- Date, Isao;
- Sonoda, Yukihiko
Publication type:
Article
N-terminal region of α-synuclein is essential for the fatty acid-induced oligomerization of the molecules
Published in:
FEBS Letters, 2008, v. 582, n. 25/26, p. 3693, doi. 10.1016/j.febslet.2008.10.001
By:
- Karube, Hiroki;
- Sakamoto, Masahiro;
- Arawaka, Shigeki;
- Hara, Susumu;
- Sato, Hiroyasu;
- Ren, Chang-Hong;
- Goto, Saori;
- Koyama, Shingo;
- Wada, Manabu;
- Kawanami, Toru;
- Kurita, Keiji;
- Kato, Takeo
Publication type:
Article
Monoamine Oxidase-B Inhibition Facilitates α-Synuclein Secretion In Vitro and Delays Its Aggregation in rAAV-Based Rat Models of Parkinson's Disease.
Published in:
Journal of Neuroscience, 2021, v. 41, n. 35, p. 7479, doi. 10.1523/JNEUROSCI.0476-21.2021
By:
- Yoshitsugu Nakamura;
- Shigeki Arawaka;
- Hiroyasu Sato;
- Asuka Sasaki;
- Taro Shigekiyo;
- Kazue Takahata;
- Hiroko Tsunekawa;
- Takeo Kato
Publication type:
Article
Eosinophilic granulomatosis with polyangiitis complicated by subarachnoid hemorrhage and coronary vasculitis: a case report and review of the literature.
Published in:
2018
By:
- Matsuda, Shogo;
- Yoshida, Shuzo;
- Fujiki, Youhei;
- Satomi, Hidetoshi;
- Takeuchi, Tohru;
- Hirose, Yoshinobu;
- Makino, Shigeki;
- Arawaka, Shigeki
Publication type:
Case Study
Efficacy and safety of combination therapy with prednisolone and oral tacrolimus for progressive interstitial pneumonia with systemic sclerosis: A retrospective study.
Published in:
Modern Rheumatology, 2018, v. 28, n. 6, p. 1009, doi. 10.1080/14397595.2018.1441658
By:
- Junichi Konma;
- Takuya Kotani;
- Takeshi Shoda;
- Takayasu Suzuka;
- Youhei Fujiki;
- Koji Nagai;
- Kenichiro Hata;
- Shuzo Yoshida;
- Tohru Takeuchi;
- Shigeki Makino;
- Shigeki Arawaka
Publication type:
Article
GRK5‐mediated inflammation and fibrosis exert cardioprotective effects during the acute phase of myocardial infarction.
Published in:
FEBS Open Bio, 2023, v. 13, n. 2, p. 380, doi. 10.1002/2211-5463.13551
By:
- Nagasaka, Akiomi;
- Terawaki, Tsuyoshi;
- Noda, Makoto;
- Takashima, Miyuki;
- Fujino, Mika;
- Yamauchi, Yuto;
- Arawaka, Shigeki;
- Kato, Takeo;
- Nakaya, Michio
Publication type:
Article
Correction: Serum matrix metalloproteinase 3 levels are associated with an effect of iguratimod as add-on therapy to biological DMARDs in patients with rheumatoid arthritis.
Published in:
2019
By:
- Tokai, Nao;
- Yoshida, Shuzo;
- Kotani, Takuya;
- Yoshikawa, Ayaka;
- Kimura, Yuko;
- Fujiki, Youhei;
- Matsumura, Yoko;
- Takeuchi, Tohru;
- Makino, Shigeki;
- Arawaka, Shigeki
Publication type:
Correction Notice
Serum matrix metalloproteinase 3 levels are associated with an effect of iguratimod as add-on therapy to biological DMARDs in patients with rheumatoid arthritis.
Published in:
PLoS ONE, 2018, p. 1, doi. 10.1371/journal.pone.0202601
By:
- Tokai, Nao;
- Yoshida, Shuzo;
- Kotani, Takuya;
- Yoshikawa, Ayaka;
- Kimura, Yuko;
- Fujiki, Youhei;
- Matsumura, Yoko;
- Takeuchi, Tohru;
- Makino, Shigeki;
- Arawaka, Shigeki
Publication type:
Article
The role of Ser129 phosphorylation of α-synuclein in neurodegeneration of Parkinson's disease: a review of in vivo models.
Published in:
Reviews in the Neurosciences, 2013, v. 24, n. 2, p. 115, doi. 10.1515/revneuro-2012-0071
By:
- Sato, Hiroyasu;
- Kato, Takeo;
- Arawaka, Shigeki
Publication type:
Article
Clinical features of Guillain-Barré syndrome patients with elevated serum creatine kinase levels.
Published in:
2020
By:
- Hosokawa, Takafumi;
- Nakajima, Hideto;
- Sawai, Taiki;
- Nakamura, Yoshitsugu;
- Sano, Eri;
- Tsukahara, Akihiro;
- Unoda, Kiichi;
- Ishida, Shimon;
- Sakane, Sadaki;
- Kimura, Fumiharu;
- Arawaka, Shigeki
Publication type:
journal article
Fulminant Guillain-Barré syndrome showing severe pharyngeal-cervical-brachial weakness in the recovery phase: a case report.
Published in:
2019
By:
- Nakamura, Yoshitsugu;
- Motoki, Mikiko;
- Hirose, Takahiko;
- Hosokawa, Takafumi;
- Ishida, Shimon;
- Arawaka, Shigeki
Publication type:
journal article
Potential of Cellular and Animal Models Based on a Prion-Like Propagation of α-Synuclein for Assessing Antiparkinson Agents.
Published in:
Molecular Neurobiology, 2015, v. 52, n. 1, p. 226, doi. 10.1007/s12035-014-8858-7
By:
- Sato, Hiroyasu;
- Kato, Takeo;
- Arawaka, Shigeki
Publication type:
Article
UBR5 Gene Mutation Is Associated with Familial Adult Myoclonic Epilepsy in a Japanese Family.
Published in:
2012
By:
- Kato, Takeo;
- Tamiya, Gen;
- Koyama, Shingo;
- Nakamura, Tomohiro;
- Makino, Satoshi;
- Arawaka, Shigeki;
- Kawanami, Toru;
- Tooyama, Ikuo
Publication type:
Journal Article
UBR5 Gene Mutation Is Associated with Familial Adult Myoclonic Epilepsy in a Japanese Family.
Published in:
ISRN Neurology, 2012, p. 1, doi. 10.5402/2012/508308
By:
- Kato, Takeo;
- Tamiya, Gen;
- Koyama, Shingo;
- Nakamura, Tomohiro;
- Makino, Satoshi;
- Arawaka, Shigeki;
- Kawanami, Toru;
- Tooyama, Ikuo
Publication type:
Article
A comprehensive study of repetitive transcranial magnetic stimulation in Parkinson's disease.
Published in:
2011
By:
- Kimura, Hideki;
- Kurimura, Masayuki;
- Kurokawa, Katsurou;
- Nagaoka, Utako;
- Arawaka, Shigeki;
- Wada, Manabu;
- Kawanami, Toru;
- Kurita, Keiji;
- Kato, Takeo
Publication type:
Journal Article
A Comprehensive Study of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease.
Published in:
ISRN Neurology, 2011, p. 1, doi. 10.5402/2011/845453
By:
- Kimura, Hideki;
- Kurimura, Masayuki;
- Kurokawa, Katsurou;
- Nagaoka, Utako;
- Arawaka, Shigeki;
- Wada, Manabu;
- Kawanami, Toru;
- Kurita, Keiji;
- Kato, Takeo
Publication type:
Article
Authentically Phosphorylated α-Synuclein at Ser129 Accelerates Neurodegeneration in a Rat Model of Familial Parkinson’s Disease.
Published in:
Journal of Neuroscience, 2011, v. 31, n. 46, p. 16884, doi. 10.1523/jneurosci.3967-11.2011
By:
- Hiroyasu Sato;
- Shigeki Arawaka;
- Susumu Hara;
- Shingo Fukushima;
- Kaori Koga;
- Shingo Koyama;
- Takeo Kato
Publication type:
Article

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