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- Title
A Novel Route for the.
- Authors
Lashkari, Mojtaba; Maghsoodlou, Malek Taher; Hazeri, Nourallah; Habibi ‐ Khorassani, Sayyed Mostafa; Akbarzadeh Torbati, Niloufar; García ‐ Granda, Santiago; Torre ‐ Fernández, Laura
- Abstract
A protocol has been developed for the synthesis of dispiro[tetrahydroquinoline-bis(2,2-dimethyl[1,3] dioxane-4,6-dione)] derivatives via a one-pot domino of arylamines, aromatic aldehydes, and Meldrum's acid for the first time. The products, with remarkable diastereoselectivity, were successfully synthesized in media in ambient temperature along with the suggested mechanism through combination of domino Knoevenagel, Michael, and . The products have been characterized by IR, mass, 1H NMR, 13C NMR spectroscopy, and elemental analyses. The stereoselectivity of compounds was established with crystallography and NMR spectroscopy.
- Subjects
QUINOLINE; DIOXANE; AROMATIC amines; AROMATIC aldehydes; STEREOSELECTIVE reactions; SPECTRUM analysis
- Publication
Journal of Heterocyclic Chemistry, 2015, Vol 52, Issue 3, p873
- ISSN
0022-152X
- Publication type
Article
- DOI
10.1002/jhet.1984